What Are the Early Symptoms of Medullary Thyroid Cancer?

Medullary thyroid cancer (MTC) is a rare form of thyroid cancer that originates in the C cells of the thyroid gland. Early detection is crucial for effective treatment, so recognizing the initial symptoms is important. Here are the early symptoms associated with medullary thyroid cancer:

1. Thyroid Nodules: One of the most common early signs of MTC is the presence of a thyroid nodule. These nodules may be felt as a lump in the neck, and while not all nodules are cancerous, any persistent lump should be evaluated by a healthcare professional.

2. Neck Swelling: Swelling in the neck is another early symptom. As the cancer grows, it may cause noticeable swelling, leading to discomfort and changes in the appearance of the neck.

3. Changes in Voice: Medullary thyroid cancer can affect the nerves around the thyroid gland, potentially leading to hoarseness or changes in voice. If you notice persistent changes in your voice, especially if accompanied by a lump or swelling, consult a doctor.

4. Difficulty Swallowing: As a tumor progresses, it may press against the esophagus or trachea, leading to difficulty swallowing or breathing. This symptom should not be ignored and warrants immediate medical attention.

5. Persistent Cough: A chronic cough that does not improve may signal a problem with the thyroid or nearby structures. While coughing can be due to many conditions, a persistent cough alongside other symptoms should be discussed with a healthcare provider.

6. Elevated Calcium Levels: Medullary thyroid cancer can cause increased production of calcitonin, leading to elevated calcium levels in the blood. Symptoms of high calcium levels may include nausea, vomiting, constipation, and abdominal pain. If any of these symptoms arise, it’s essential to seek medical advice.

7. Family History: People with a family history of medullary thyroid cancer, particularly those with multiple endocrine neoplasia type 2 (MEN2) syndrome, should be vigilant for any unusual symptoms. Genetic testing and regular monitoring may be recommended.

If you experience any of these early symptoms or have concerns about medullary thyroid cancer, it is crucial to consult with a healthcare provider. Early diagnosis and intervention can significantly improve outcomes. Regular check-ups and monitoring are essential for those at higher risk.